Pharmaceutical Medicines

Product Details:

Vatozic-P Tab (ACECLOFENAC 100MG PARACETAMOL 325MG)

Aceclofenac is a phenylacetic acid derivative that inhibits synthesis of the inflammatory cytokines interleukin-1b and tumour necrosis factor, and inhibits prostaglandin E2 production. It increases (GAG) synthesis, the principal macromolecule of the extracellular matrix, which aids in repair and regeneration of articular cartilage. Thus, aceclofenac has +ve effects on cartilage anabolism combined with modulating effect of matrix catabolism. Paracetamol has analgesic and antipyretic action with weak anti-inflammatory activity. It produces analgesia by increasing pain threshold and antipyresis by acting on the hypothalamic heat-regulating centre.

Absorption
Aceclofenac Rapidly absorbed almost 100% bioavailability peak plasma levels reached about 1.25-3 hours after oral admin.

Distribution
Aceclofenac >99.7% bound to plasma proteins distributes into synovial fluid. Paracetamol Distributes throughout most fluids of the body.

Metabolism
Aceclofenac Probably metabolised by CYP2C9 average plasma elimination half-life 4-4.3 hours. Paracetamol Mainly metabolised hepatically plasma elimination half-life 1-4 hours.

Excretion
Aceclofenac About two-thirds of the administered dose is removed in the urine, mainly as conjugated hydroxymetabolites. Paracetamol Most metabolites are removed in the urine within 24 hours.

Product Details:

Cinnarizine is used to treat problems affecting the inner ear and balance, such as dizziness and sickness. It is also helpful in preventing travel sickness.

Nerves situated inside your ear send messages to your brain with information about your movement. If the nerves in one of your ears send too many, too few, or wrong messages to your brain, it conflicts with the messages sent from your other ear, your eyes, or your body. Your brain then gets confused and this can cause dizziness and a spinning sensation (vertigo), this is what causes you to feel sick.

Travel sickness is caused by repeated unusual movements during travelling. These repeated movements, such as going over bumps or around in a circle, send lots of messages to your brain.

Cinnarizine helps reduce the feelings of sickness and vertigo caused by problems such as these. It is available on prescription, or you can buy it without a prescription at a pharmacy. It can be taken by adults and by children over the age of 5 years.

Before taking cinnarizine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking cinnarizine it is important that your doctor knows

If you are pregnant or breast-feeding.

If you have prostate problems, or have been experiencing difficulty passing urine.

If you have any problems with the way your liver works or with the way your kidneys work.

If you have any of the following conditions increased pressure in your eye (glaucoma), epilepsy, or Parkinsons disease.

If you think you may have a blockage in your intestines.

If you have a rare inherited blood disorder called porphyria.

If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.

If you have ever had an allergic reaction to a medicine.

How to take cinnarizine
Take cinnarizine exactly as your doctor or pharmacist tells you to. It is usually taken three times daily.

If you are taking cinnarizine to prevent travel sickness, take the first dose two hours before you are due to travel. If you are going on a long journey, you can then take further doses every eight hours if needed. If you are giving cinnarizine to a child, check the label carefully to make sure you are giving the correct dose for the age of your child. Make sure you leave eight hours between each dose.

If you are able, take cinnarizine after a meal or with a snack.

Product Details:

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Product Details:

Levocetirizine 5 Mg Montelukast 10mg
Valevo- M

Montelukast is used to prevent and treat asthma, seasonal and year round allergies (hay fever), and prevent exercise-induced asthma. It blocks the action of certain natural substances (leukotrienes) that are involved in causing asthma and allergies.Levocetirizine is used to treat symptoms of allergic conditions such as allergic fever (hay fever), year-round allergies like dust or pet allergies and chronic nettle rash.

Additional Information:

• Packaging Details: PACK: ALU/ALU PACKING: 10X10

Product Details:

This medication is used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin . It works by stopping the growth of bacteria.This treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu).

Product Details:

Glimepiride stimulates the insulin release from functioning pancreatic -cells and inhibits gluconeogenesis at hepatic cells. It also increases insulin sensitivity at peripheral target sites. Metformin decreases hepatic gluconeogenesis, decreases intestinal absorption of glucose and improves insulin sensitivity (increases peripheral glucose uptake and utilisation).

Glimepiride + Metformin Adverse Reactions / Glimepiride + Metformin Side Effects

Diarrhoea, vomiting, metallic taste, rash, isolated transaminase elevations, cholestatic jaundice, allergic skin reactions, photosensitivity reactions, leukopaenia, agranulocytosis, thrombocytopaenia, haemolytic anaemia, aplastic anaemia, pancytopaenia, blurred vision.

Potentially Fatal Lactic acidosis.

Special Precautions

Renal and hepatic impairment. Avoid alcohol consumption. Hypoglycaemic episodes.

Other Drug Interactions

Concomitant admin with increases Cmax, AUC, and T1/2 of glimepiride. increases the mean AUC of glimepiride. increases the Cmax of metformin.

Potentially Fatal NSAIDS, salicylates, sulfonamides, chloramphenicol, coumarins, , MAOs, and beta blockers potentiate the hypoglycemic action of glimepiride.

Dosage

Oral
Type 2 diabetes mellitus
Adult Per tablet contains glimepiride 1 mg and metformin 250 mg or glimepiride 2 mg and metformin 500 mg Take as directed. Titrate according to response.

Product Details:

Aceclofenac 100mg Tablets

Anti-inflammatory painkillers like aceclofenac are also called non-steroidal anti-inflammatory drugs (NSAIDs), or sometimes just 'anti-inflammatories'. Aceclofenac is prescribed for people with painful rheumatic conditions such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis

Product Details:

Ofloxacin 200 Mg Tablets
Valflox-200

Ofloxacin is given to treat a bacterial infection. It is useful for treating infections such as chest infections, urine infections, skin and soft tissue infections, and some transmitted infections. Some infections can be treated with a single tablet, others require a course of treatment lasting a week or so. Ofloxacin works by killing the bacteria which are the cause of the infection.

Before taking ofloxacin Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking ofloxacin it is important that your doctor knows

If you are pregnant, trying for a baby, or breast-feeding.

If you are under 18 years of age.

If you have ever experienced a problem with your tendons, called tendonitis.

If you have any problems with the way your kidneys work, or if you have a problem with your liver.

If you have epilepsy or any other condition that causes fits.

If you have a heart condition, or if you have been told you have an unusual heartbeat.

If you have a condition causing tired and weak muscles, called myasthenia gravis.

If you know you have glucose 6-phosphate dehydrogenase (G6PD) deficiency. This is a genetic disorder which causes problems after eating foods such as fava beans.

If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.

How to take ofloxacin

Before you start taking the tablets, read the manufacturer's printed information leaflet from inside the pack. The manufacturer's leaflet will give you more information about ofloxacin and a full list of the side-effects which you may experience from taking it.

Take ofloxacin exactly as your doctor tells you to. The usual dose is one 200 mg or 400 mg tablet taken daily. For some types of infection, however, you may be asked to take two doses a day. Read the label carefully to make sure you know what dose is right for you.

If you are taking one dose a day, it is preferable to take it in the morning. If you are taking more than one dose a day, try to space out your doses - so ideally, take a tablet every 12 hours.

You can take ofloxacin before or after meals. Many people find it helps to swallow the tablets with a drink of water.

 

Product Details:

Cefpodoxime 200 Mg & Ofloxacin Tablets
Valmep-o

Cefpodoxime is a cephalosporin antiboitic with similar structure as that of . It is used in the treatment of certain bacterial infections in the body like urinary tract infection, transmitted disease (gonorrhea), lung infection (pneumonia), kidney infection (pyelonephritis), sinusitis, skin or soft tissue Infection, inflammation of tonsils (tonsillitis), sore throat (pharyngitis), and upper respiratory tract infection.How it worksIt works by interfering with the formation of the outer covering (cell wall) of bacteria so that the wall ruptures and results in the death of the bacteria.

Ofloxacin(200 Mg)

Ofloxacin is used to treat bacterial infections including upper and lower urinary tract infections, lower respiratory tract infections, skin and soft tissue infections and transmitted infections (of urethra and cervix).

Additional Information:

• Item Code: 90
• Production Capacity: Any
• Delivery Time: 7-10 days

Product Details:

Aceclofenac 100 Mg
Vatozik-100 Tab

Aceclofenac film-coated tablets are indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

Aceclofenac film-coated tablets are supplied for oral administration and should be swallowed whole with a sufficient quantity of liquid.

To be taken preferably with or after food. When Aceclofenac was administered to fasting and fed healthy volunteers only the rate and not the extent of aceclofenac absorption was affected.

Undesirable effects may be minimized by using the lowest effective dose for the shortest duration necessary to control symptoms.

The recommended dose is 200 mg daily, taken as two separate 100 mg doses, one tablet in the morning and one in the evening.

Paediatric population

There are no clinical data on the use of Aceclofenac in children and therefore it is not recommended for use in children under 18 years of age.

Product Details:

Ferrous Ascorbate & Folic Acid, a synthetic form of iron and vitamin C is prescribed for pregnant women to prevent spina bifida in an unborn fetus, to improve iron utilization and to prevent folate or iron deficiency anemia.

Pharmacodynamics

Ferrous ascorbate is a synthetic form of iron and vitamin C. Iron is recycled by the body and produce erythroid precursor cells. Exogenous administration of folic acid is essential for normal erythropoiesis process. Folic acid is vital for the biosynthesis of purines and thymidylate of nucleic acids. Defective purine biosynthesis due to folate deficiency leads to megaloblastic anemia and macrocytic anemia.

Pharmacokinetics

Ferrous Ascorbate:
After oral administration, the iron is predominantly absorbed in the upper jejunum and duodenum. About 90% of the administered dose is bound to plasma proteins. The iron as ferrous forms binds with transferrin and transported to the spleen, liver and bone marrow. The GI absorption of iron is very low due to systemic recycling of iron. About 1 mg/day of endogenous iron is eliminated in the urine, skin and feces.

Folic acid:

Folic acid is rapidly absorbed in the proximal portion of the small intestine. After oral administration, the Cmax can be achieved within one hour. As tetrahydrofolic acid derivative, folic acid is well-distributed in all over the body tissues and stored in hepatic tissues. Folic acid is metabolized in liver into dihydrofolate and tetrahydrofolate forms. About 90% of the administered dose is excreted via the urine.

Precautions

Ferrous ascorbate+Folic acid is contraindicated in patients with iron supplements allergy, patients with hemosiderosis, haemolytic anemia, active infections and hemochromatosis.

Other Drug Interactions

Ferrous ascorbate+Folic acid may interact with , diphenylhydantoin, primidone, tetracycline group of drugs, quinolones, penicillamine, L-dopa, methyldopa, bisphosphonates and calcium salts.

Food(before/after)

Ferrous ascorbate+Folic acid can be taken before or after food intake

Product Details:

Diclofenac Sodium & Paracetamol Tablet is used for Back pain, Sprains and strains, Headache, Fever, Febrility, Tooth ache, Joint pain, Cold, Cephalalgia, Ear pain, Toothache and other conditions. Diclofenac Sodium & Paracetamol Tablet may also be used for purposes not listed in this medication guide.

Additional Information:

• Packaging Details: BLISTER, 20X10

Product Details:

Paracetamol 650 Mg
Velcin- 650

Paracetamol belongs to a group of medicines known as analgesics, or painkillers. It is used to relieve mild-to-moderate pain. It is also useful for lowering a raised temperature (fever), such as after childhood immunisation.

Paracetamol is a common painkiller and is available to buy from many retail outlets as tablets/capsules and as liquid medicine. Many brands of over-the-counter combination painkillers contain paracetamol, as do many cold and flu remedies. It is important that you check the label on any preparation that you buy to make sure that you are not taking more than one preparation containing paracetamol.

Before taking paracetamol

Most people can take paracetamol without any problem, but to make sure it is the right treatment for you, speak with a doctor or pharmacist before you start taking it if

You are pregnant or breast-feeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.

You have a serious problem with the way your liver works, or if you regularly drink large amounts of alcohol.

You are taking medicines prescribed by a doctor.

You have ever had an allergic reaction to a medicine.

Additional Information:

• Packaging Details: Pack:Blister Packing 10x10

Product Details:

Ciprofloxacin 500 Mg

Ciprofloxacin is an in a group of drugs called fluoroquinolones (flor-o-KWIN-o-lones). Ciprofloxacin fights bacteria in the body.

Ciprofloxacin is used to treat different types of bacterial infections. It is also used to treat people who have been exposed to anthrax.

Important information

You should not use this medication if you are also taking tizanidine.

You may not be able to use ciprofloxacin if you have a muscle disorder. Tell your doctor if you have a history of myasthenia gravis.

Ciprofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles tendon of the heel. This effect may be more likely to occur if you are over 60, if you take steroid medication, or if you have had a kidney, heart, or lung transplant.

Stop taking this medicine and call your doctor at once if you have sudden pain, swelling, bruising, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions.

Product Details:

Azithromycin 250 Mg Tablets

Azithromycin is an antibiotic that fights bacteria.

Azithromycin is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases.

Azithromycin may also be used for purposes not listed in this medication guide.

Important information

You should not use azithromycin if you have ever had jaundice or liver problems when you have previously taken this medicine.

Before taking this medicine

You should not use azithromycin if you are allergic to it, or if

you have ever had jaundice or liver problems caused by taking azithromycin or

you are allergic to similar drugs such as clarithromycin, erythromycin, or telithromycin.

To make sure azithromycin is safe for you, tell your doctor if you have

liver disease

kidney disease

myasthenia gravis

a heart rhythm disorder or

a history of Long QT syndrome.

This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether azithromycin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Do not give this medicine to a child younger than 6 months old.

Product Details:

Cefixime 200mg Clav Pot 125mg
Valnux-clav
Cefixime 200mg + Clavulanic acid 125mg: Cefixime Uses Include Treatment Of Soft Tissue Infection , Lower And Upper Respiratory Tract Infections And Other Infections . Cefixime Is Used Alone Or In Combination With Class Of Anti-Biotics For Better Coverage .

Additional Information:

• Packaging Details: PACK: ALU ALU PACKING 10X10

Product Details:

Aceclofenac, Paracetamol & Chlorzoxaxone Tablets

PACK: BLISTER
PACKING: 20X10

Product Details:

Ofloxacin 200 mg Ornidazole 500 mg
Valflox- Z

Ofloxacin + Ornidazole tablets, used to treat serious bacterial infections. Ofloxacin is a quinolone _antibiotic used for treating certain kinds of bacterial infections. Ornidazole is a Nitroimidazole which is an antibacterial and antiprotozoal drug used to treat anaerobic enteric protozoa. It has

· Excellent penetration into body fluids & tissues

· Superior efficacy in polymicrobial infections.

· Absorption not hampered by food

Indications

· Mixed Diarrhoea.

· Post-operative infections

· Respiratory tract infections

· Gynaecological infections

· Diabetic foot infections

Product Details:

Amoxycillin & Clavulanic Tablets
The combination of amoxicillin and clavulanic acid is used to treat certain infections caused by bacteria, including infections of the ears, lungs, sinus, skin, and urinary tract. Amoxicillin is in a class of medications called penicillin-like antibiotics. It works by stopping the growth of bacteria.

Product Details:

Cefuroxime 500 Mg Tablets
Cefuroxime is used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu).

Product Details:

Levocetirizine Hydrochloride IP 5 Mg
Vevop
Levocetirizine is an antihistamine used to relieve allergy symptoms such as wateryeyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.

How to use levocetirizine

Take this medication by mouth with or without food as directed by your doctor, usually once daily in the evening.

If you are using the liquid form of this medication, measure the dose carefully using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this medication more often than directed.

Tell your doctor if your condition does not improve or if it worsens.

Product Details:

Paracetamol 325 MG Diclo 50 MG
VALDAC-P TAB

Diclofenac is used to relieve pain and swelling (inflammation) from various mild to moderate painful conditions. It is used to treat muscle aches, backaches, dental pain, menstrual cramps, and sports injuries. It also reduces pain, swelling, and joint stiffness caused by arthritis. Paracetamol or acetaminophen USAN, is a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer). It is commonly used for the relief of headaches and other minor aches and pains.